ORAHS2024
Abstract Submission

267. Research Perspectives and Areas for Improvement in the Production of Blood Components from Donated Units

Contributed abstract in session TB-3: Humanitarian Logistics and Blood Supply, stream Regular talks.

Tuesday, 11:00-12:30
Room: Room S2

Authors (first author is the speaker)

1. Ettore Lanzarone
DIGIP, University of Bergamo
2. Aleyna Gürsoy
University of Bergamo
3. ROBERTO PINTO
Management, Information and Production Engineering, University of Bergamo
4. Federico Piccinini
Delcon
5. Davide Ghezzi
Delcon
6. Silvano Rossini
Niguarda Hospital

Abstract

Blood is a vital resource for health care, but at the same time limited in that it can only be obtained from donations made by healthy individuals. The Blood Donation Supply Chain (BDSC) is responsible for managing the demand and supply of blood and blood component units, and consists of four echelons: collection, production, storage, and distribution. We focus on the production/separation of blood components (including erythrocytes, plasma, platelets and cryoprecipitates) from whole blood units, which is the least studied BDSC echelon in the literature. Generally, this separation is a make-to-stock process, and alternative fractionation sequences can be used to produce blood components from whole blood units.
We address this production echelon from a scheduling perspective, which, to the best of our knowledge, has not been done so far in the literature. We first analyse the Immunohematology and Transfusion Medicine Department of the Niguarda Hospital, Milan, Italy. Then, we extend our analysis to a general class of systems and compare the European and US systems.
Based on these analyses and a literature review, we evaluate future research directions to improve the management of this production system. In particular, we map the production of blood components within the de-manufacturing sector, to analyse the approaches applied in this sector that can also be effective for this special production.

Keywords

Status: accepted


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