2917. Evaluating the Cost-Effectiveness of Transitioning from Metered-Dose Inhalers to Dry Powder Inhalers for Asthma Management: A System Dynamics Approach
Invited abstract in session TC-11: Emergency care and services, stream OR in Healthcare (ORAHS).
Tuesday, 12:30-14:00Room: Clarendon SR 1.03
Authors (first author is the speaker)
| 1. | Armando Vargas-Palacios
|
| AUHE, University of Leeds |
Abstract
Abstract
Objectives: This paper aims to reduce CO2 emissions by evaluating the cost-effectiveness of replacing Metered-Dose Inhalers (MDIs) with Dry Powder Inhalers (DPIs) for asthma management in the UK. This involves assessing the impact on direct and indirect healthcare costs and patient outcomes across the asthma care pathway.
Methods: A System Dynamics (SD) model built to simulate the transition from MDIs to DPIs, considering parameters like disease severity, treatment adherence, symptom control, and healthcare resource use. The cost-effectiveness analysis concentrated on direct costs, such as medication and hospitalisations, excluding indirect costs like CO2 emissions and lost productivity.
Results: Switching from MDI to DPIs may result in a potential loss of symptom control. While the base scenario (0% loss in symptom control) shows an additional cost of £0.29 per unit of CO2 saved by using DPIs, and no extra medical expenses. However, a 10% loss in symptom control raises the cost to £0.33 per CO2 unit saved, leading to a loss of 0.002 QALYs per patient and adds £72.41 to annual treatment costs per patient.
Conclusion: The model shows that economic, environmental, and patient factors affect the cost-effectiveness of switching from MDIs to DPIs. While DPIs may provide long-term savings and environmental benefits, a successful transition requires managing higher initial costs and potential temporary loss of symptom control for some patients.
Keywords
- Behavioural OR
- Simulation
- Health Care
Status: accepted
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